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Gallbladder events rise modestly, especially with rapid loss. Less common signals include skin dysesthesia, which is now on the label, and a small thyroid-cancer association from two different instruments: a nested case-control study and an RCT meta-analysis, both on a small absolute event base. Depression and suicidality remain unproven
As we age, our ability to recover from physical activity tends to slow down, which can lead to longer periods of soreness and fatigue
This needs to be directly assessed in future research, alongside any reductions in use
Jayappa et al., 2023)
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